Last reviewed 2026-05-06 by the Canadian Anabolics editorial team.
What is Zionova MK 677 (Ibutamoren)?
MK-677 (Ibutamoren mesylate) is an orally active non-peptidic growth hormone secretagogue. It mimics ghrelin at the GHSR receptor to stimulate the body’s own pituitary GH and IGF-1 release, rather than supplying exogenous somatropin. Reported half-life is approximately ~24 hours, supporting once-daily oral dosing. It is offered at Canadian Anabolics in the Weight Loss collection, stocked in a Canadian warehouse for tracked domestic shipping.
Specifications at a glance
| Property | Value |
|---|---|
| Compound class | Oral growth hormone secretagogue (non-peptidic) |
| Derivative | Ibutamoren mesylate |
| Mechanism | Ghrelin-receptor (GHSR) agonist |
| Half-life | ~24 hours |
| Form | Oral tablet |
| Brand | Zionova |
Sealed by Zionova — a premium house brand stocked at Canadian Anabolics. See the full Zionova brand catalogue for tier context.
Shipping and notes
Orders dispatch from a Canadian warehouse in plain unmarked packaging with tracked delivery, typically 2–5 business days within Canada. Age verification (18+) is required at checkout. Commonly reported effects include increased appetite and mild fluid retention; do not stack with other GH-axis compounds or insulin without medical advice.
Adult-use compounds. Sales restricted to adults 18 or older. MK-677 may transiently raise fasting glucose and reduce insulin sensitivity — do not use if you have diabetes or impaired glucose tolerance without medical supervision. Products are not approved by Health Canada for over-the-counter sale and are not intended to diagnose, treat, cure or prevent any disease. Consult a licensed healthcare professional before use. Plain unmarked packaging on dispatch. Canadian Anabolics makes no medical or therapeutic claims.


